Sporadic ALS has compartment-specific aberrant exon splicing and altered cell–matrix adhesion biology

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive weakness from loss of motor neurons. The fundamental pathogenic mechanisms are unknown and recent evidence is implicating a significant role for abnormal exon splicing and RNA processing. Using new...

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Bibliografiska uppgifter
Huvudupphovsmän: Rabin, Stuart J., Kim, Jae Mun ‘Hugo’, Baughn, Michael, Libby, Ryan T., Kim, Young Joo, Fan, Yuxin, Libby, Randell T., La Spada, Albert, Stone, Brad, Ravits, John
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796893/
https://ncbi.nlm.nih.gov/pubmed/19864493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp498
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