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Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds
A full understanding of the proteome will require ligands to all of the proteins encoded by genomes. While antibodies represent the principle affinity reagents used to bind proteins, their limitations have created a need for new ligands to large numbers of proteins. Here we propose a general concept...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796340/ https://ncbi.nlm.nih.gov/pubmed/19894711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9051735 |
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