Site-specific semisynthetic variant of human hemoglobin.
A single round of Edman degradation was employed to remove the NH2-terminal valine from isolated alpha chains of human hemoglobin. Reconstitution of normal beta chains with truncated or substituted alpha chains was used to form truncated (des-Val1-alpha 1) and substituted ([[1-13C]Gly1]alpha 1) tetr...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.709 |
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