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Induction of Neuronal Vascular Endothelial Growth Factor Expression by cAMP in the Dentate Gyrus of the Hippocampus Is Required for Antidepressant-Like Behaviors

The cAMP cascade and vascular endothelial growth factor (VEGF) are critical modulators of depression. Here we have tested whether the antidepressive effect of the cAMP cascade is mediated by VEGF in the adult hippocampus. We used a conditional genetic system in which the Aplysia octopamine receptor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jeong-Sik, Jang, Deok-Jin, Lee, Nuribalhae, Ko, Hyoung-Gon, Kim, Hyoung, Kim, Yong-Seok, Kim, Byungwoo, Son, Junehee, Kim, Sung Hyun, Chung, Heekyoung, Lee, Mun-Yong, Kim, Woon Ryoung, Sun, Woong, Zhuo, Min, Abel, Ted, Kaang, Bong-Kiun, Son, Hyeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796224/
https://ncbi.nlm.nih.gov/pubmed/19571140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1321-09.2009
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