Induction of Neuronal Vascular Endothelial Growth Factor Expression by cAMP in the Dentate Gyrus of the Hippocampus Is Required for Antidepressant-Like Behaviors

The cAMP cascade and vascular endothelial growth factor (VEGF) are critical modulators of depression. Here we have tested whether the antidepressive effect of the cAMP cascade is mediated by VEGF in the adult hippocampus. We used a conditional genetic system in which the Aplysia octopamine receptor...

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Autori principali: Lee, Jeong-Sik, Jang, Deok-Jin, Lee, Nuribalhae, Ko, Hyoung-Gon, Kim, Hyoung, Kim, Yong-Seok, Kim, Byungwoo, Son, Junehee, Kim, Sung Hyun, Chung, Heekyoung, Lee, Mun-Yong, Kim, Woon Ryoung, Sun, Woong, Zhuo, Min, Abel, Ted, Kaang, Bong-Kiun, Son, Hyeon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796224/
https://ncbi.nlm.nih.gov/pubmed/19571140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1321-09.2009
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