Evaluation of genetic risk scores for lipid levels using genome-wide markers in the Framingham Heart Study

BACKGROUND: Multiple single-nucleotide polymorphisms have been associated with low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels. In this paper, we evaluate a weighted and an unweighted approach for estimating the combined effect...

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Hauptverfasser: Piccolo, Stephen R, Abo, Ryan P, Allen-Brady, Kristina, Camp, Nicola J, Knight, Stacey, Anderson, Jeffrey L, Horne, Benjamin D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
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Proceedings
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795945/
https://ncbi.nlm.nih.gov/pubmed/20018038
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