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Pedigree association: assigning individual weights to pedigree members for genetic association analysis

OBJECTIVE: Methods exist to appropriately perform association analyses in pedigrees. However, for genome-wide association analysis, these methods are computationally impractical. It is therefore important to determine alternate methods that can be efficiently used genome-wide. Here, we introduce a n...

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Hlavní autoři: Knight, Stacey, Abo, Ryan P, Wong, Jathine, Thomas, Alun, Camp, Nicola J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795894/
https://ncbi.nlm.nih.gov/pubmed/20017987
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