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Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood-ratio test and conditional score statistic

Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a specific phenotype. Because linkage and association analysis provide complementary...

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Bibliographic Details
Main Authors: Hendricks, Audrey E, Zhu, Yanyan, Dupuis, Josée
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795871/
https://ncbi.nlm.nih.gov/pubmed/20017964
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