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A unified framework for linkage and association analysis of quantitative traits
We give a unified treatment of the statistical foundations of population based association mapping and of family based linkage mapping of quantitative traits in humans. A central ingredient in the unification involves the efficient score statistic. The discussion focuses on generalized linear models...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2154410/ https://ncbi.nlm.nih.gov/pubmed/18077372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707138105 |
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