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A unified framework for linkage and association analysis of quantitative traits

We give a unified treatment of the statistical foundations of population based association mapping and of family based linkage mapping of quantitative traits in humans. A central ingredient in the unification involves the efficient score statistic. The discussion focuses on generalized linear models...

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Detalhes bibliográficos
Main Authors: Dupuis, Josée, Siegmund, David O., Yakir, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154410/
https://ncbi.nlm.nih.gov/pubmed/18077372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707138105
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