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A Unified Haseman-Elston Method for Testing Linkage with Quantitative Traits

The Haseman and Elston (H-E) method uses a simple linear regression to model the squared trait difference of sib pairs with the shared allele identical by descent (IBD) at marker locus for linkage testing. Under this setting, the squared mean-corrected trait sum is also linearly related to the IBD s...

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Detalhes bibliográficos
Main Authors: Xu, Xin, Weiss, Scott, Xu, Xiping, Wei, L. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287874/
https://ncbi.nlm.nih.gov/pubmed/10961909
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