Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II

Elevated expression of insulin-like growth factor II (IGF-II) is frequently observed in a variety of human malignancies, including breast, colon and liver cancer. As IGF-II can deliver a mitogenic signal through both the type 1 insulin-like growth factor receptor (IGF-IR) and an alternately spliced...

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Autores principales: Newman, Janet, Cohen, Edward H., Cosgrove, Leah, Kopacz, Kris, Dransfield, Daniel T., Adams, Timothy E., Peat, Thomas S.
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2009
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795608/
https://ncbi.nlm.nih.gov/pubmed/19724140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109024932
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