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Expression, purification, crystallization and preliminary X-ray analysis of the HER3–9E12 Fab complex

9E12 is a fully human immunoglobulin G(1)/κ monoclonal antibody that is specific for the epidermal growth factor receptor 3 (HER3), the overexpression of which has been detected in many tumour types and is associated with poor survival outcomes. To date, knowledge of the molecular mechanism for targ...

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שמור ב:
מידע ביבליוגרפי
Main Authors: He, Kecheng, Huang, Ang, Huang, Yong, Takeda, Hiroaki
פורמט: Artigo
שפה:Inglês
יצא לאור: International Union of Crystallography 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051538/
https://ncbi.nlm.nih.gov/pubmed/24915094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14008917
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