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Expression, purification, crystallization and preliminary X-ray analysis of the HER3–9E12 Fab complex
9E12 is a fully human immunoglobulin G(1)/κ monoclonal antibody that is specific for the epidermal growth factor receptor 3 (HER3), the overexpression of which has been detected in many tumour types and is associated with poor survival outcomes. To date, knowledge of the molecular mechanism for targ...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
International Union of Crystallography
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051538/ https://ncbi.nlm.nih.gov/pubmed/24915094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14008917 |
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