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Crystallization and preliminary X-ray diffraction studies of the ubiquitin-like (UbL) domain of the human homologue A of Rad23 (hHR23A) protein

Human homologue A of Rad23 (hHR23A) plays dual roles in DNA repair as well as serving as a shuttle vehicle targeting polyubiquitinated proteins for degradation. Its N-terminal ubiquitin-like (UbL) domain interacts with the 19S proteasomal cap and provides the docking mechanism for protein delivery....

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Detalhes bibliográficos
Main Authors: Chen, Yu Wai, Tajima, Toshitaka, Rees, Martin, Garcia-Maya, Mitla
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795604/
https://ncbi.nlm.nih.gov/pubmed/19724136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109031376
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