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The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid
Adenylosuccinate lyase (ASL) is an enzyme from the purine-biosynthetic pathway that catalyzes the cleavage of 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) to 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) and fumarate. ASL is also responsible for the conversion of succi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795585/ https://ncbi.nlm.nih.gov/pubmed/19724117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109029674 |
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