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Edgetic perturbation models of human inherited disorders

Cellular functions are mediated through complex systems of macromolecules and metabolites linked through biochemical and physical interactions, represented in interactome models as ‘nodes' and ‘edges', respectively. Better understanding of genotype-to-phenotype relationships in human disea...

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Autors principals: Zhong, Quan, Simonis, Nicolas, Li, Qian-Ru, Charloteaux, Benoit, Heuze, Fabien, Klitgord, Niels, Tam, Stanley, Yu, Haiyuan, Venkatesan, Kavitha, Mou, Danny, Swearingen, Venus, Yildirim, Muhammed A, Yan, Han, Dricot, Amélie, Szeto, David, Lin, Chenwei, Hao, Tong, Fan, Changyu, Milstein, Stuart, Dupuy, Denis, Brasseur, Robert, Hill, David E, Cusick, Michael E, Vidal, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795474/
https://ncbi.nlm.nih.gov/pubmed/19888216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.80
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