Edgetic perturbation models of human inherited disorders

Cellular functions are mediated through complex systems of macromolecules and metabolites linked through biochemical and physical interactions, represented in interactome models as ‘nodes' and ‘edges', respectively. Better understanding of genotype-to-phenotype relationships in human disea...

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Main Authors: Zhong, Quan, Simonis, Nicolas, Li, Qian-Ru, Charloteaux, Benoit, Heuze, Fabien, Klitgord, Niels, Tam, Stanley, Yu, Haiyuan, Venkatesan, Kavitha, Mou, Danny, Swearingen, Venus, Yildirim, Muhammed A, Yan, Han, Dricot, Amélie, Szeto, David, Lin, Chenwei, Hao, Tong, Fan, Changyu, Milstein, Stuart, Dupuy, Denis, Brasseur, Robert, Hill, David E, Cusick, Michael E, Vidal, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795474/
https://ncbi.nlm.nih.gov/pubmed/19888216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.80
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