Edgetic perturbation models of human inherited disorders

Cellular functions are mediated through complex systems of macromolecules and metabolites linked through biochemical and physical interactions, represented in interactome models as ‘nodes' and ‘edges', respectively. Better understanding of genotype-to-phenotype relationships in human disea...

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Detalhes bibliográficos
Main Authors: Zhong, Quan, Simonis, Nicolas, Li, Qian-Ru, Charloteaux, Benoit, Heuze, Fabien, Klitgord, Niels, Tam, Stanley, Yu, Haiyuan, Venkatesan, Kavitha, Mou, Danny, Swearingen, Venus, Yildirim, Muhammed A, Yan, Han, Dricot, Amélie, Szeto, David, Lin, Chenwei, Hao, Tong, Fan, Changyu, Milstein, Stuart, Dupuy, Denis, Brasseur, Robert, Hill, David E, Cusick, Michael E, Vidal, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795474/
https://ncbi.nlm.nih.gov/pubmed/19888216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.80
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