Self-production of tissue factor-coagulation factor VII complex by ovarian cancer cells

BACKGROUND: Thromboembolic events are a major complication in ovarian cancer patients. Tissue factor (TF) is frequently overexpressed in ovarian cancer tissue and correlates with intravascular thrombosis. TF binds to coagulation factor VII (fVII), changing it to its active form, fVIIa. This leads to...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yokota, N, Koizume, S, Miyagi, E, Hirahara, F, Nakamura, Y, Kikuchi, K, Ruf, W, Sakuma, Y, Tsuchiya, E, Miyagi, Y
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2009
विषय:
Molecular Diagnostics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795428/
https://ncbi.nlm.nih.gov/pubmed/19904262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605406
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