Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study

BACKGROUND: We evaluated bevacizumab with metronomic etoposide among recurrent malignant glioma patients in a phase 2, open-label trial. METHODS: A total of59 patients, including 27 with glioblastoma (GBM) and 32 with grade 3 malignant glioma, received 10 mg kg(−1) bevacizumab biweekly and 50 mg m(−...

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Main Authors: Reardon, D A, Desjardins, A, Vredenburgh, J J, Gururangan, S, Sampson, J H, Sathornsumetee, S, McLendon, R E, Herndon, J E, Marcello, J E, Norfleet, J, Friedman, A H, Bigner, D D, Friedman, H S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Clinical Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795427/
https://ncbi.nlm.nih.gov/pubmed/19920819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605412
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