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Agonist efficacy and receptor desensitization: from partial truths to a fuller picture
It has been demonstrated that the degree of agonist-induced desensitization of the β(2)-adrenoceptor is related to agonist efficacy (strength of signalling), whereby high-efficacy agonists (e.g. formoterol) cause more phosphorylation and internalization of the receptor than low-efficacy agonists (e....
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795257/ https://ncbi.nlm.nih.gov/pubmed/19719779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00352.x |
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