Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation

X-linked chronic granulomatous disease (X-CGD) is an inherited immunodeficiency with absent phagocyte NADPH oxidase activity caused by defects in the gene encoding gp91(phox). Here we evaluated strategies for less intensive conditioning for gene therapy of genetic blood disorders without selective a...

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Detalhes bibliográficos
Main Authors: Sadat, Mohammed A., Dirscherl, Sara, Sastry, Lakshmi, Dantzer, Jessica, Pech, Nancy, Griffin, Samantha, Hawkins, Troy, Zhao, Yiqiang, Barese, Cecilia N., Cross, Scott, Orazi, Attilio, An, Caroline, Goebel, W. Scott, Yoder, Mervin C., Li, Xiaoman, Grez, Manuel, Cornetta, Kenneth, Mooney, Sean D., Dinauer, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795029/
https://ncbi.nlm.nih.gov/pubmed/19657370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.96
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