Enhanced homing and engraftment of fresh but not ex vivo cultured murine marrow cells in submyeloablated hosts following CD26 inhibition by Diprotin A

OBJECTIVE: We recently reported that murine marrow cultured ex vivo for gamma-retrovirus transduction engrafts ~10 fold less well than fresh marrow upon transplantation into submyeloablated hosts. Here, we evaluated homing efficiency as a potential mechanism for this engraftment disparity, and wheth...

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Autori principali: Wyss, Brandon K., Donnelly, Abigail F. W., Zhou, Dan, Sinn, Anthony L., Pollok, Karen E., Goebel, W. Scott
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700780/
https://ncbi.nlm.nih.gov/pubmed/19540435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.03.005
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