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VEGF and IHH Rescue Definitive Hematopoiesis in Gata-4 and Gata-6 Deficient Murine Embryoid Bodies

OBJECTIVE: Murine embryonic stem (ES) cells can be differentiated into embryoid bodies (EBs), which serve as an in vitro model recapitulating many aspects of embryonic yolk sac hematopoiesis. Differentiation of ES cells deficient in either Gata-4 or Gata-6 results in EBs with disrupted visceral endo...

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Main Authors: Pierre, Monique, Yoshimoto, Momoko, Huang, Lan, Yoder, Mervin C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727578/
https://ncbi.nlm.nih.gov/pubmed/19501129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.05.011
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