DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression

High-level expression of the human growth hormone (hGH) gene is limited to somatotrope and lactosomatotrope cells of the anterior pituitary. We previously identified a locus control region (LCR) for the hGH gene composed of four tissue-specific DNase I-hypersensitive sites (HS) located between −14.6...

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Hauptverfasser: Bennani-Baïti, Idriss M., Asa, Sylvia L., Song, Decheng, Iratni, Rabah, Liebhaber, Stephen A., Cooke, Nancy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27950/
https://ncbi.nlm.nih.gov/pubmed/9724759
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