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Characterization of a key neutralizing epitope on pertussis toxin recognized by the monoclonal antibody 1B7

Despite over five decades of research and vaccination, infection by Bordetella pertussis remains a serious disease with no specific treatments or validated correlates of protective immunity. Of the numerous monoclonal antibodies binding pertussis toxin (PTx) that have been produced and characterized...

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Bibliographic Details
Main Authors: Sutherland, Jamie N, Maynard, Jennifer A
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794999/
https://ncbi.nlm.nih.gov/pubmed/19899804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901532z
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