Characterization of murine monoclonal antibodies that recognize defined epitopes of pertussis toxin and neutralize its toxic effect on Chinese hamster ovary cells.

Three murine monoclonal antibodies (MAb), E19, E205, and E251, raised against pertussis toxin reacted in Western blots (immunoblots) with the S1, S4, and S2-S3 subunits, respectively, and neutralized the Chinese hamster ovary cell-clustering activity of pertussis toxin. MAb E251 recognized a linear...

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Pubblicato in:	Infect Immun
Autori principali:	Walker, M J, Wehland, J, Timmis, K N, Raupach, B, Schmidt, M A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1718872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.11.4249-4251.1991
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