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Hypoxia in high glucose followed by reoxygenation in normal glucose reduces the viability of cortical astrocytes through increased permeability of connexin 43 hemichannels

Brain ischemia causes more extensive injury in hyperglycemic than normoglycemic subjects, and the increased damage is to astroglia as well as neurons. In the present work, we found that in cortical astrocytes from rat or mouse, reoxygenation after hypoxia in a medium mimicking interstitial fluid dur...

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Detalhes bibliográficos
Main Authors: Orellana, Juan A., Hernández, Diego E., Ezan, Pascal, Velarde, Victoria, Bennett, Michael V. L., Giaume, Christian, Sáez, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794960/
https://ncbi.nlm.nih.gov/pubmed/19705457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20926
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