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Cx43 Hemichannels and Gap Junction Channels in Astrocytes Are Regulated Oppositely by Proinflammatory Cytokines Released from Activated Microglia

Astrocytes have a role in maintaining normal neuronal functions, some of which depend on connexins, protein subunits of gap junction channels and hemichannels. Under inflammatory conditions, microglia release cytokines, including interleukin-1β and tumor necrosis factor-α, that reduce intercellular...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Retamal, Mauricio A., Froger, Nicolas, Palacios-Prado, Nicolas, Ezan, Pascal, Sáez, Pablo J., Sáez, Juan C., Giaume, Christian
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673621/
https://ncbi.nlm.nih.gov/pubmed/18077690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2042-07.2007
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