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Withaferin A Targets Heat Shock Protein 90 in Pancreatic Cancer Cells

The purpose of this study is to investigate the efficacy and the mechanism of Hsp90 inhibition of Withaferin A (WA), a steroidal lactone occurring in Withania somnifera, in pancreatic cancer in vitro and in vivo. Withaferin A exhibited potent antiproliferative activity against pancreatic cancer cell...

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Detalhes bibliográficos
Main Authors: Yu, Yanke, Hamza, Adel, Zhang, Tao, Gu, Mancang, Zou, Peng, Newman, Bryan, Li, Yanyan, Leslie Gunatilaka, A. A., Whitesell, Luke, Zhan, Chang-Guo, Sun, Duxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794909/
https://ncbi.nlm.nih.gov/pubmed/19769945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.09.017
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