Epidermal Growth Factor Receptor Translocation to the Mitochondria: REGULATION AND EFFECT

Co-overexpression of the epidermal growth factor (EGF) receptor (EGFR) and c-Src frequently occurs in human tumors and is linked to enhanced tumor growth. In experimental systems this synergistic growth requires EGF-dependent association of c-Src with the EGFR and phosphorylation of Tyr-845 of the r...

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Detalhes bibliográficos
Main Authors: Demory, Michelle L., Boerner, Julie L., Davidson, Robert, Faust, William, Miyake, Tsuyoshi, Lee, Icksoo, Hüttemann, Maik, Douglas, Robert, Haddad, Gabriel, Parsons, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794774/
https://ncbi.nlm.nih.gov/pubmed/19840943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000760
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