Gadd45a Expression Induces Bim Dissociation from the Cytoskeleton and Translocation to Mitochondria

Gadd45a, a p53- and BRCA1-regulated stress protein, has been implicated in the maintenance of genomic fidelity, probably through its roles in the control of cell cycle checkpoint and apoptosis. However, the mechanism(s) by which Gadd45a is involved in the induction of apoptosis remains unclear. We s...

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Detalhes bibliográficos
Main Authors: Tong, Tong, Ji, Junfang, Jin, Shunqian, Li, Xianxing, Fan, Wenhong, Song, Yongmei, Wang, Minrong, Liu, Zhihua, Wu, Min, Zhan, Qimin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140626/
https://ncbi.nlm.nih.gov/pubmed/15899854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4488-4500.2005
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