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Integrin Activation Dynamics between the RGD-binding Site and the Headpiece Hinge

Integrins form mechanical links between the extracellular matrix and the cytoskeleton. Although integrin activation is known to be regulated by an allosteric conformational change, which can be induced from the extracellular or intracellular end of the molecule, little is known regarding the sequenc...

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書目詳細資料
Main Authors: Puklin-Faucher, Eileen, Vogel, Viola
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794771/
https://ncbi.nlm.nih.gov/pubmed/19762919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041194
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