The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding

Human type 3 adenovirus dodecahedron (a virus like particle made of twelve penton bases) features the ability to enter cells through Heparan Sulphate Proteoglycans (HSPGs) and integrins interaction and is used as a versatile vector to deliver DNA or proteins. Cryo-EM reconstruction of the pseudovira...

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Bibliographic Details
Main Authors: Gout, E., Schoehn, G., Fenel, D., Lortat-Jacob, H., Fender, P.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833306/
https://ncbi.nlm.nih.gov/pubmed/20224646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/541939
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