Neuropeptide Y Knockout Mice Reveal a Central Role of NPY in the Coordination of Bone Mass to Body Weight

Changes in whole body energy levels are closely linked to alterations in body weight and bone mass. Here, we show that hypothalamic signals contribute to the regulation of bone mass in a manner consistent with the central perception of energy status. Mice lacking neuropeptide Y (NPY), a well-known o...

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Detalhes bibliográficos
Main Authors: Baldock, Paul A., Lee, Nicola J., Driessler, Frank, Lin, Shu, Allison, Susan, Stehrer, Bernhard, Lin, En-Ju D., Zhang, Lei, Enriquez, Ronald F., Wong, Iris P. L., McDonald, Michelle M., During, Matthew, Pierroz, Dominique D., Slack, Katy, Shi, Yan C., Yulyaningsih, Ernie, Aljanova, Aygul, Little, David G., Ferrari, Serge L., Sainsbury, Amanda, Eisman, John A., Herzog, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794533/
https://ncbi.nlm.nih.gov/pubmed/20027231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008415
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