Critical Role of Arcuate Y4 Receptors and the Melanocortin System in Pancreatic Polypeptide-Induced Reduction in Food Intake in Mice

BACKGROUND: Pancreatic polypeptide (PP) is a potent anti-obesity agent known to inhibit food intake in the absence of nausea, but the mechanism behind this process is unknown. METHODOLOGY/PRINCIPAL FINDINGS: Here we demonstrate that in response to i.p. injection of PP in wild type but not in Y4 rece...

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Detalhes bibliográficos
Main Authors: Lin, Shu, Shi, Yan-Chuan, Yulyaningsih, Ernie, Aljanova, Aygul, Zhang, Lei, Macia, Laurence, Nguyen, Amy D., Lin, En-Ju Deborah, During, Matthew J., Herzog, Herbert, Sainsbury, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796177/
https://ncbi.nlm.nih.gov/pubmed/20041129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008488
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