Cystin Localizes to Primary Cilia via Membrane Microdomains and a Targeting Motif

Primary cilia are dynamic, complex structures that contain >500 proteins, including several related to polycystic kidney disease. How these proteins target to cilia and assemble is unknown. We previously identified Cys1 as the gene responsible for disease in Cys1(cpk) mice, a mouse model of autos...

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Detalhes bibliográficos
Main Authors: Tao, Binli, Bu, Su, Yang, Zhihua, Siroky, Brian, Kappes, John C., Kispert, Andreas, Guay-Woodford, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794227/
https://ncbi.nlm.nih.gov/pubmed/19850956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009020188
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