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Cystin Localizes to Primary Cilia via Membrane Microdomains and a Targeting Motif

Primary cilia are dynamic, complex structures that contain >500 proteins, including several related to polycystic kidney disease. How these proteins target to cilia and assemble is unknown. We previously identified Cys1 as the gene responsible for disease in Cys1(cpk) mice, a mouse model of autos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tao, Binli, Bu, Su, Yang, Zhihua, Siroky, Brian, Kappes, John C., Kispert, Andreas, Guay-Woodford, Lisa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794227/
https://ncbi.nlm.nih.gov/pubmed/19850956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009020188
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