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Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs
Silencing specificity is a critical issue in the therapeutic applications of siRNA, particularly in the treatment of single nucleotide polymorphism (SNP) diseases where discrimination against single nucleotide variation is demanded. However, no generally applicable guidelines are available for the d...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794185/ https://ncbi.nlm.nih.gov/pubmed/19815667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp835 |
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