MGMT Promoter Methylation Is Prognostic but Not Predictive for Outcome to Adjuvant PCV Chemotherapy in Anaplastic Oligodendroglial Tumors: A Report From EORTC Brain Tumor Group Study 26951

PURPOSE: O6-methylguanine-methyltransferase (MGMT) promoter methylation has been shown to predict survival of patients with glioblastomas if temozolomide is added to radiotherapy (RT). It is unknown if MGMT promoter methylation is also predictive to outcome to RT followed by adjuvant procarbazine, l...

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Detalhes bibliográficos
Main Authors: van den Bent, Martin J., Dubbink, Hendrikus J., Sanson, Marc, van der Lee-Haarloo, Cathleen R., Hegi, Monika, Jeuken, Judith W.M., Ibdaih, Ahmed, Brandes, Alba A., Taphoorn, Martin J.B., Frenay, Marc, Lacombe, Denis, Gorlia, Thierry, Dinjens, Winand N.M., Kros, Johan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793037/
https://ncbi.nlm.nih.gov/pubmed/19901104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.24.1034
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