MGMT Promoter Methylation Is Prognostic but Not Predictive for Outcome to Adjuvant PCV Chemotherapy in Anaplastic Oligodendroglial Tumors: A Report From EORTC Brain Tumor Group Study 26951

PURPOSE: O6-methylguanine-methyltransferase (MGMT) promoter methylation has been shown to predict survival of patients with glioblastomas if temozolomide is added to radiotherapy (RT). It is unknown if MGMT promoter methylation is also predictive to outcome to RT followed by adjuvant procarbazine, l...

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Bibliografski detalji
Glavni autori: van den Bent, Martin J., Dubbink, Hendrikus J., Sanson, Marc, van der Lee-Haarloo, Cathleen R., Hegi, Monika, Jeuken, Judith W.M., Ibdaih, Ahmed, Brandes, Alba A., Taphoorn, Martin J.B., Frenay, Marc, Lacombe, Denis, Gorlia, Thierry, Dinjens, Winand N.M., Kros, Johan M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2009
Teme:
Original Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793037/
https://ncbi.nlm.nih.gov/pubmed/19901104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.24.1034
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