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Dissecting the Role of Critical Residues and Substrate Preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis

Newly emerging multi-drug resistant strains of Mycobacterium tuberculosis (M.tb) severely limit the treatment options for tuberculosis (TB); hence, new antitubercular drugs are urgently needed. The mymA operon is essential for the virulence and intracellular survival of M.tb and thus represents an a...

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Hlavní autoři: Khare, Garima, Gupta, Vibha, Gupta, Rakesh K., Gupta, Radhika, Bhat, Rajiv, Tyagi, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793005/
https://ncbi.nlm.nih.gov/pubmed/20027301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008387
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