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Attenuation of Mycobacterium tuberculosis functionally disrupted in a fatty acyl-CoA synthetase gene fadD5

One key adaptation that Mycobacterium tuberculosis established to survive long term in vivo is a reliance on lipids as an energy source. M. tuberculosis H37Rv has 36 fadD genes annotated as putative fatty acyl-CoA synthetase genes, which encode enzymes that activate fatty acids for metabolism. One s...

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Detalhes bibliográficos
Main Authors: Dunphy, Kathleen Y., Senaratne, Ryan H., Masuzawa, Mamiko, Kendall, Lon V., Riley, Lee W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225055/
https://ncbi.nlm.nih.gov/pubmed/20214478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/651452
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