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Characterization of Cofactor-Induced Folding Mechanism of a Zinc Binding Peptide Using Computationally Designed Mutants

Metals are the most commonly encountered protein cofactors, and they play important structural and functional roles in biology. In many cases, metal-binding provides a major driving force for a polypeptide chain to fold. While there are many studies on the structure, stability, and function of metal...

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Detalhes bibliográficos
Main Authors: Tang, Jia, Kang, Seung-Gu, Saven, Jeffery G., Gai, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792901/
https://ncbi.nlm.nih.gov/pubmed/19361525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.074
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