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Fluorescence Correlation Spectroscopic Study of Serpin Depolymerization by Computationally Designed Peptides
Members of the serine proteinase inhibitor (serpin) family play important roles in the inflammatory and coagulation cascades. Interaction of a serpin with its target proteinase induces a large conformational change, resulting in insertion of its reactive center loop (RCL) into the main body of the p...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995557/ https://ncbi.nlm.nih.gov/pubmed/17442346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.042 |
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