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Fluorescence Correlation Spectroscopic Study of Serpin Depolymerization by Computationally Designed Peptides

Members of the serine proteinase inhibitor (serpin) family play important roles in the inflammatory and coagulation cascades. Interaction of a serpin with its target proteinase induces a large conformational change, resulting in insertion of its reactive center loop (RCL) into the main body of the p...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Chowdhury, Pramit, Wang, Wei, Lavender, Stacey, Bunagan, Michelle R., Klemke, Jason W., Tang, Jia, Saven, Jeffrey G., Cooperman, Barry S., Gai, Feng
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995557/
https://ncbi.nlm.nih.gov/pubmed/17442346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.042
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