The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

The transcription factor E2F plays a major role in cell cycle control in mammalian cells. E2F binding sites, which are present in the promoters of a variety of genes required for S phase, shift from a negative to a positive role in transcription at the commitment point, a crucial point in G(1) that...

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Bibliographic Details
Main Authors: Ferreira, Roger, Magnaghi-Jaulin, Laura, Robin, Philippe, Harel-Bellan, Annick, Trouche, Didier
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC27922/
https://ncbi.nlm.nih.gov/pubmed/9724731
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