Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

Many disease-associated variants identified by genome-wide association (GWA) studies are expected to regulate gene expression. Allele-specific expression (ASE) quantifies transcription from both haplotypes using individuals heterozygous at tested SNPs. We performed deep human transcriptome-wide rese...

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Autors principals: Heap, Graham A., Yang, Jennie H.M., Downes, Kate, Healy, Barry C., Hunt, Karen A., Bockett, Nicholas, Franke, Lude, Dubois, Patrick C., Mein, Charles A., Dobson, Richard J., Albert, Thomas J., Rodesch, Matthew J., Clayton, David G., Todd, John A., van Heel, David A., Plagnol, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792152/
https://ncbi.nlm.nih.gov/pubmed/19825846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp473
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