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Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease

Huntington's disease (HD) is a late-onset neurodegenerative disorder that is characterized neuropathologically by the presence of neuropil aggregates and nuclear inclusions. However, the profile of aggregate structures that are present in the brains of HD patients or of HD mouse models and the...

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Hlavní autoři: Sathasivam, Kirupa, Lane, Amin, Legleiter, Justin, Warley, Alice, Woodman, Ben, Finkbeiner, Steve, Paganetti, Paolo, Muchowski, Paul J., Wilson, Stuart, Bates, Gillian P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792149/
https://ncbi.nlm.nih.gov/pubmed/19825844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp467
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