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Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease

Huntington's disease (HD) is a late-onset neurodegenerative disorder that is characterized neuropathologically by the presence of neuropil aggregates and nuclear inclusions. However, the profile of aggregate structures that are present in the brains of HD patients or of HD mouse models and the...

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Main Authors: Sathasivam, Kirupa, Lane, Amin, Legleiter, Justin, Warley, Alice, Woodman, Ben, Finkbeiner, Steve, Paganetti, Paolo, Muchowski, Paul J., Wilson, Stuart, Bates, Gillian P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2010
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792149/
https://ncbi.nlm.nih.gov/pubmed/19825844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp467
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